N-乙酰半胱氨酸治疗小儿支气管肺炎的疗效分析

目的：探究N-乙酰半胱氨酸对小儿支气管肺炎的治疗效果。方法随机选取2012年8月-2013年12月在该院就诊的100例小儿支气管肺炎患者,随机分为A、B两组,各50例,A组采用盐酸氨溴索治疗,B组采用N-乙酰半胱氨酸治疗,比较两组的有效率、肺部啰音减少时间和咳嗽消失时间以及不良反应。结果B组有效率96%明显高于A组82%,差异有统计学意义(P<0.05);B组肺部啰音减少时间(4.12±1.23)d明显短于A组(6.87±1.69)d,B组咳嗽消失时间(4.31±1.46)d明显短于A组(6.84±1.42)d,差异有统计学意义(P<0.05);两组的不良反应发生率分别为7.5%、5%,差异无统计学意义(P>0.05)。结论 N-乙酰半胱氨酸对于治疗小儿支气管肺炎有显著疗效,可以缩短肺部啰音减少时间,值得推广。

Efficacy of N-acetylcysteine in Treatment of Children with Bronchial Pneu-monia

Objective To explore the effect of N- acetyl cysteine on treatment of children with bronchial pneumonia. Methods Random selection 100 cases of children with bronchial pneumonia from August 2012 to December 2013 were ran-domly divided into group A, group B two groups.group A were treated with ambroxol hydrochloride,group B were treated with N-acetylcysteine,Compared of the efficiency of the two groups, pulmonary rales reduce time.Results The efficiency of group B 96%was significantly higher than that in group A 82%, the difference was statistically significant (P<0.05);the pul-monary rales reduce time of group B (4.12 ±1.23) d significantly shorter than group A(6.87±1.69) d, The disappearance time of cough in group B (4.31±1.46)d was significantly shorter than that in group A (6.84±1.42) d,the difference was statistical-ly significant (P<0.05);The incidence of adverse reactions in the two groups was 7.5%,5%, and the difference was not statistically significant(P>0.05). Conclusion N- acetylcysteine has remarkable curative effect for the treatment of children with bronchial pneumonia, pulmonary rales can shorten the reduction time, worthy of promotion.