米非司酮治疗子宫内膜异位症的疗效及其机制分析

目的：分析米非司酮治疗子宫内膜异位症的疗效及其机制。方法方便选取该院2014年2月-2015年4月收治的90例子宫内膜异位症患者,经随机双盲的方式,分成观察组和对照组,各45例。观察组通过米非司酮治疗,对照组通过孕三烯酮治疗,对比两组临床疗效。结果观察组的治疗总有效率93.33%,对照组的治疗总有效率80%,差异具有统计学意义,P<0.05。观察组和对照组的复发率分别为：4.44%、24.44%,组间比较,差异有统计学意义,P<0.05。两组不良反应情况、治疗前、后性激素比较,差异均具有统计学意义,P<0.05。结论子宫内膜异位症,通过米非司酮治疗,临床疗效确切,且复发率较低,值得方面广泛应用和推广。

Analysis of the Therapeutic Effect and Mechanism of Mifepristone in the Treatment of Endometriosis

Objective To analyze the curative effect of treatment of endometriosis and its mechanism of mifepristone. Methods Convenient select our hospital from February 2014 to April 2015 were the 90 examples of intrauterine membrane in patients with endometriosis, by the way, randomized, double-blind, divided into observation group and control group, 45 cases each. Observation group was treated with mifepristone, the control group treated by gestrinone, compared two groups of clinical curative effect. Results Treatment group total effectiveness 93.33%, control group total effective rate of 80%, the difference is statistically significant, P < 0.05. The recurrence rate of observation group and control group were: 4.44%, 24.44%, the comparison between groups, significant difference, P< 0.05. Two groups of adverse situation, treatment before and after sex hormones, differences were statistically significant, P< 0.05. Conclusion Endometriosis by mifepristone treat-ment, clinical efficacy and lower recurrence rate, worthy of wide application and promotion.