坎地沙坦联合贝那普利治疗原发性高血压及其对患者血脂的影响

目的：探讨坎地沙坦联合贝那普利治疗原发性高血压及对改善血脂的临床疗效。方法：将118例患者随机分为试验组与对照组，对照组使用贝那普利治疗，试验组在对照组治疗基础上加用坎地沙坦，比较两组降压效果、血脂改变及不良反应情况。结果：两组治疗前后收缩压、舒张压、脉压差、血脂各指标均有明显降低，试验组明显优于对照组，比较差异均具有统计学意义（P〈0.05）。两组降压有效率分别为93.2%和81.4%，比较差异有统计学意义（P〈0.05）。且试验组不良反应较小，停药后能逐渐恢复。结论：坎地沙坦联合贝那普利治疗原发性高血压疗效好、不良反应小，且能显著改善患者血脂，值得临床推广应用。

Candesartan Combined with Benazepril Treatment of Essential Hypertension and its Impact on the Blood Lipid

Objective：To explore the clinical efficacy of candesartan combined with benazepril to treat hypertension and improve the lipids. Method：118 cases of patients were randomly divided into the experimental group and the control group,the control group was given benazepril treatment,the experimental group was given plus candesartan treatment on the basis of the control group,antihypertensive effect of alterations in lipids, and adverse reactions were compared.Result：Before and after treatment systolic blood pressure,diastolic blood pressure,pulse pressure,blood lipid indexes were significantly lower,the experimental group was significantly better than the control group,the results were statistically significant（P〈0.05）. Two sets of buck efficiency of 93.2%and 81.4%respectively,results were statistically significant（P〈0.05）.And the experimental group less adverse reactions,gradually recovered after discontinuation.Conclusion：Candesartan combined with benazepril treat hypertension with good efficacy,little adverse reactions,and can significantly improve the lipids,worthy of promotion.