我院2011-2014年35 665例呼吸道感染患儿肺炎支原体抗体检测结果分析

目的:探讨呼吸道感染患儿肺炎支原体(MP)感染的规律与特点。方法:选取我院2011-2014年收治的呼吸道感染患儿35 665例,检测血清MP抗体,采用回顾性研究方法分析MP抗体阳性率在不同性别、年龄、季节、病种间的差异,并随访观察患儿MP抗体的转阴时间。结果:呼吸道感染患儿血清MP抗体总体阳性率为14.6%,其中呼吸道感染患儿血清MP抗体阳性率性别比较差异有统计学意义,女性(17.4%)高于男性(12.4%,P<0.01);年龄比较差异有统计学意义(P<0.01),以7~9岁组最高(23.9%);季节比较差异有统计学意义(P<0.01),以冬季(12月至次年2月)最高(17.1%),夏季(6-8月)最低(10.8%);病种比较差异有统计学意义(P<0.01),以大叶性肺炎最高(72.0%),急性上呼吸道感染最低(7.0%)。患儿MP抗体转阴时间集中在首次检测确诊后3~9个月。结论:MP是儿童呼吸道感染主要病原之一,呼吸道感染患儿血清MP抗体总体阳性率为14.6%,女性高于男性;MP感染多见于大叶性肺炎,以7~9岁组患儿多见,冬季高发;MP感染患儿MP抗体转阴时间集中在首次检测确诊后3~9个月。

Mycoplasma Pneumoniae Antibody Testing Results Analysis of 35,665 Children with Respiratory Tract Infection in Our Hospital, 2011-2014

Objective: To explore the characteristics and laws of Mycoplasma pneumoniae (MP) infection. Methods: MP antibodies were detected in 35,665 children with respiratory infection from 2011 to 2014, and the collected data were analyzed by the method of retrospective control study. Results: Among the 35,665 samples, the positive rate was 14.6%. The positive rate of male was 12.4% while the female was 17.4%, there was a significant difference among the gender (P<0.01). There was a significant difference in the infection rate of different age groups (P<0.01). The positive rate of 7 to 9 years old children accounted for 23.9% that was higher than the others. MP infection occurred in the whole year. The positive rates of winter were higher than the other seasons. There was a significant difference in the diseases (P<0.01). The proportion of lobar pneumonia was highest, accounted for 72.0%, acute upper respiratory tract infection was lowest, accounted for 7.0%. The average time of positive MP antibody reversing to negative were 3 to 9 months. Conclusion: Among respiratory infections, MP infection is the major cause for children especially 7 to 9 years old. It occurs more in female and often occur in winter. The average time of positive MP antibody reversing to negative are 3 to 9 months.