|
|||||
|
|
| 依酚氯铵的合成 | |
| 引用本文： | 芦金荣,莫莉蓉. 依酚氯铵的合成[J]. 中国医药工业杂志, 2000, 31(6): 243-244 |
| 作者姓名： | 芦金荣 莫莉蓉 |
| 作者单位： | 中国药科大学有机化学教研室，江苏南京 210009 |
| 摘 要： | 以间氨基苯酚为起始原料，经Ｎ－甲基化、季铵化，再与氧化银作用后以盐酸中和，制得依酚氯铵，总收率３１．２％，对甲基化反应和季铵化反应均作了改进，使之更适合于生产。 |
| 关 键 词： | 依酚氯胺 季铵化 合成 |
| 文章编号： | 1001-8255(2000)06-0243-02 |
| 修稿时间： | 1999-06-15 |
Synthesis of Edrophonium Chloride |
|
| LU Jin Rong,MO Li Rong. Synthesis of Edrophonium Chloride[J]. , 2000, 31(6): 243-244 | |
| Authors: | LU Jin Rong MO Li Rong |
| Abstract: | Edrophonium chloride (1) was synthesized from N ethyl N (m hydroxyphenyl) dimethylammonium bromide (6) which was prepared from 3 aminophenol through methylation with dimethyl sulfate and quaternization with ethyl bromide.The overall yield was 31.2%. |
| Keywords: | edrophonium chloride quaternization synthesis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |