局部注射A型肉毒毒素治疗Meige综合征

目的 观察A型肉毒毒素(BTX—A)治疗Meige综合征，(眼睑痉挛-口颌肌张力障碍综合征)的疗效。方法 用A型肉毒毒素对17例Meige综合征行面部肌肉局部多点注射，分析其治疗结果。结果 17例中完全缓解者9例，明显缓解者5例，部分缓解者2例，无效1例。总有效率94％。起效时间数小时至3天，疗效持续时间3～6个月。局部副反应轻微、短暂，无全身反应及过敏反应。结论 A型肉毒毒素是治疗Meige综合征最有效的方法。

Local injection of botulinum toxin type A in the treatment of meige''''s syndrome

Objective To study the efficacy of botulinum A toxin injection for the treat ment of Meige's syndrome. Methods A total of 17patients were evaluated on therapeutic efficacy of multifocal facial injection. Results Of the 9 patients were completly relieved,5 remarkably relieved,2 partial relieved and 1 had no improvement;94% of the patients experienced relief. Clinical observation showed marked improvement in symptoms from a few hours to the 3 day after injection and lasted about 3 to 6 months. The local side effects were transient and mild,no systemic adverse and allegic reactions were noted. Conclusion Boutlinu A toxin local injection was the best method of treatment meige's syndrome.