早发型重度子痫前期并发低蛋白血症的临床分析

目的:探讨低蛋白血症对早发型重度子痫前期妊娠结局的影响.方法·对98例早发型重度子痫前期患者的临床资料进行分析总结,按是否发生低蛋白血症分为低蛋白血症组和非低蛋白血症组,对其一般资料、并发症、胎儿新生儿情况进行比较.结果:早发型重度子痫前期患者合并低蛋白血症,两组治疗时间、终止妊娠孕周、入院时平均动脉血压等指标比较,差异均有统计学意义(P＜0.05),低蛋白血症组发生肝肾功能损害、胸腹水、胎盘早剥、心功能不全的发生率均高于非低蛋白血症组,差异有统计学意义.在低蛋白血症组将24h尿蛋白定量与血浆白蛋白值比较,两者间无相关性(r=-0.026,P=0.114).低蛋白血症组围生儿死亡率明显增加(P =0.000),新生儿窒息率也存在差异(P=0.037)；两组血浆白蛋白值与新生儿体重呈正相关性.结论:并发低蛋白血症是重度子痫前期病情的进一步加重,可能出现严重并发症,并可造成围生儿不良结局.

Clinical Analysis of Early Onset of Severe Preeclampsia Complicated With Hypoalbuminemia

Objective:To investigate the effect of hypoproteinemia on prenatal outcomes of pregnant women with early onset of severe preeclampsia.Methods:98cases of early onset severe pre-eclampsia patients clinical data were analyzed,then case group was divided into hypoproteinemia group and non-hypoproteinemia group.to compare the effect of difference among the two groups on the general data,complications,fetal neonatal comparison.Results:compared with two groups,the differences of the treatment duration,termination of pregnancy,gestational age at admission and mean arterial blood pressure,were statistically significant(P<0.05),hypoalbuminemia groups occurred in liver and kidney function damage,hydrothorax and ascites,placental abruption,heart failure rates are higher than the hypoproteinemia group,the difference was statistically significant.24h quantity of urinary protein and plasma albumin values of the hypoproteinemia group is no correlation(r=0.026,P=0.114).prenatal mortality rate of hypoproteinemia group increased significantly(P=0),the rate of neonatal asphyxia differences(P=0.037) ;two groups of plasma albumin values and neonatal weight positively correlated.Conclusion:Early onset of severe preeclampsia patients complicated with hypoalbuminemia prompted further aggravate the disease,may appear serious complication,and can be the cause of prenatal adverse outcomes.