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Effects of ruxolitinib cream on pruritus and quality of life in atopic dermatitis: Results from a phase 2, randomized,dose-ranging,vehicle- and active-controlled study
Affiliation:1. Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine, St Louis, Missouri;2. Incyte Corporation, Wilmington, Delaware;3. K. Papp Clinical Research and Probity Medical Research, Waterloo, Ontario, Canada;4. Wake Research Associates LLC, Raleigh, North Carolina
Abstract:
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  • Keywords:atopic dermatitis  burden of disease  itch  JAK inhibitor  Janus kinase  pruritus  quality of life  ruxolitinib  Skindex-16  AD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  atopic dermatitis  CRI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  clinically relevant improvement  JAK"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Janus kinase  MCID"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  minimal clinically important difference  NRS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  numerical rating scale  QoL"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  quality of life  RUX"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0120"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  ruxolitinib
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