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Phase 2 trial of a neurokinin-1 receptor antagonist for the treatment of chronic itch in patients with epidermolysis bullosa: A randomized clinical trial
Affiliation:1. Department of Dermatology, Stanford University School of Medicine, Redwood City, California;2. Department of Internal Medicine, University of California, Riverside, California;3. University of California, Irvine School of Medicine, Irvine, California;4. Menlo Therapeutics Inc (formerly Tigercat Pharma, Inc), Redwood City, California
Abstract:
Keywords:chronic itch  drug response  epidermolysis bullosa  neurokinin 1 receptor  NK1 receptor  NK1 receptor antagonist  pruritus  serlopitant  substance P  AE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  adverse event  EB"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  epidermolysis bullosa  NRS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Numeric Rating Scale  RDEB"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  recessive dystrophic epidermolysis bullosa  SAE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  serious adverse event  SP-NK1R"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0110"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  substance P-neurokinin 1 receptor
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