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测定胸液中D—二聚体含量的临床意义
引用本文:吕友堤 陈平. 测定胸液中D—二聚体含量的临床意义[J]. 湖南医科大学学报, 2000, 25(1): 71-72
作者姓名:吕友堤 陈平
摘    要:应用酶联免疫吸附法测定45例不同原因所致胸腔积液的D-二聚体(D-D含量)。结果示,结核性胸液与脓性胸液中D-D含量明显高于癌性胸液,且胸液中D-D含量与乳酸脱氢酶含量呈正相关。结果提示,结核性及脓性胸液纤溶活性较恶性胸液高,检测胸液中D-D含量可反映胸膜炎症反应的程度,有助于上对胸腔积液的鉴别。

关 键 词:胸膜积液 肺结核 癌症 D-二聚体 鉴别诊断

Detection of D -dimer in pleural effusion]
Y D Lü,P Chen,M Xu. Detection of D -dimer in pleural effusion][J]. Bulletin of Hunan Medical University, 2000, 25(1): 71-72
Authors:Y D Lü  P Chen  M Xu
Affiliation:Department of Internal Medicine, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Abstract:The content of D -dimer in pleural fluid of different causes was examined by the ELISA method in 45 patients. The results were that the contents of D -dimer in both tuberculous and empyema pleural effusions were significantly higher than in malignant pleural effusion (P < 0.01; P < 0.05). D -dimer was positively correlated with lactic dehydrogenase (LDH) in pleural fluid (r = 0.4168, P < 0.01). The results suggest that fibrinolytic activities in tuberculous and empyema pleural effusion are much higher than in malignant pleural effusion. The detection of D -dimer in pleural fluid may reflect the extent of pleural inflammation and be helpful in the differential diagnosis of pleural effusion.
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