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肾上腺髓质素与心血管疾病
引用本文:李利华,李燕,王继光. 肾上腺髓质素与心血管疾病[J]. 心血管病学进展, 2005, 26(3): 322-324
作者姓名:李利华  李燕  王继光
作者单位:上海第二医科大学附属瑞金医院,上海市高血压研究所,上海,200025
摘    要:
肾上腺髓质素是近年来研究较多的一种生物活性肽,具有舒张血管、利钠、利尿等多种生物活性。肾上腺髓质素广泛分布于心血管、肾脏、内分泌、呼吸等系统,以自分泌、旁分泌或内分泌形式参与这些系统的生理调节和多种疾病的病理生理过程,可能在高血压、慢性充血性心力衰竭、急性心肌梗死等疾病的临床治疗方面具有潜在的应用价值。

关 键 词:肾上腺髓质素  心血管病  高血压  充血性心力衰竭
文章编号:1004-3934(2005)03-0322-03
修稿时间:2004-08-05

Adrenomedullin and Cardiovascular Disease
LI Li-hua,LI Yan,WANG Ji-Guang. Adrenomedullin and Cardiovascular Disease[J]. Advances in Cardiovascular Diseases, 2005, 26(3): 322-324
Authors:LI Li-hua  LI Yan  WANG Ji-Guang
Abstract:
Adrenomedullin,a bioactive peptide,has been intensively studied in the last decade.It has several biological actions,such as vasodilation,natriuresis,diuresis,etc.Adrenomedullin is expressed in heart,vessels,kidney,endocrine organs and respiratory system,and plays a role in the physiological regulation and pathophysiology of diseases in these systems.Adrenomedullin might have therapeutic potential in primary hypertension,chronic congestive heart failure,and acute myocardial infarction.
Keywords:Adrenomedullin  Cardiovascular  Hypertension  Congestive heart failure
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