Probiotics in the critically ill patient: a double blind, randomized, placebo-controlled trial |
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Authors: | Damien Barraud Claire Blard François Hein Olivier Marçon Aurélie Cravoisy Lionel Nace François Alla Pierre-Edouard Bollaert Sébastien Gibot |
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Affiliation: | 1. Service de Réanimation Médicale, H?pital Central, CHU Nancy, 29 avenue du Maréchal de Lattre de Tassigny, 54035, Nancy Cedex, France 2. Centre d’Investigations Cliniques-INSERM 9501, CHU de Nancy, Nancy, France 3. Service de Réanimation polyvalente, CHG Macon, Macon, France 4. Service d’épidémiologie et d’évaluation cliniques, CHU Nancy, Nancy, France
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Abstract: |
Purpose Probiotics have been shown to be able to restore a non-pathogenic digestive flora, to prevent digestive colonization by pathogenic bacteria, and to modulate immunity. The aim of this study was to assess the effects of prophylactic probiotic administration in patients ventilated for up to 2 days. |
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