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国产左炔诺孕酮+炔雌醇片与进口对照片溶出曲线对比
引用本文:董海霞,胡媛媛. 国产左炔诺孕酮+炔雌醇片与进口对照片溶出曲线对比[J]. 按摩与康复医学, 2012, 0(21): 5-6
作者姓名:董海霞  胡媛媛
作者单位:[1]江苏省南京白敬宇制药有限责任公司,南京210038 [2]江苏先声药业有限责任公司,南京210042
摘    要:目的:国产左炔诺孕酮+炔雌醇片与进口左炔诺孕酮+炔雌醇片溶出曲线的对比。方法:本试验采用ZRS--6智能溶出试验仪,以5ug/g聚山梨酯80为溶出介质,分别测定了左炔诺孕酮+炔雌醇进口对照片与国产片的溶出曲线。结果及结论:国产左炔诺孕酮+炔雌醇片与进口左炔诺孕酮+炔雌醇片在5ug/g聚山梨酯80中溶出完全,且两者溶出曲线基本一致。

关 键 词:左炔诺孕酮+炔雌醇片  溶出度  溶出曲线

Comparison on the dissolution curve of domestic and imported Levonorgestrei and Ethinyl estradiol Tablets
Dong Haixia Hu Yuanyuan. Comparison on the dissolution curve of domestic and imported Levonorgestrei and Ethinyl estradiol Tablets[J]. Chinese Manipulation and Rehabilitation Medicine, 2012, 0(21): 5-6
Authors:Dong Haixia Hu Yuanyuan
Affiliation:Dong Haixia Hu Yuanyuan
Abstract:Objective:To make the comparison between the dissolution curve of domestic and imported Levonorgestrel and Ethinyl estradiol Tablets. Methods Intellectual diffusion meter (ZRS-6) was used to determine the dissolution curve of domestic and imported Levonorgestrel and Ethinyl estradiol Tablets. Polysorbate 80 (5ug/g) in water was used as dissolution medium. Result and Conclusion:The dissolution of the two tablets in polysorbate 80 (5ug/g) in water were complete. The dissolution curve of domestic Levonorgestrel and Ethinyl estradiol Tablets was same as that of imported ones.
Keywords:Levonorgestrel and Ethinyl estradiol Tablets Dissolution rate Dissolution curve
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