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罗格列酮对糖基化终产物干预的人肾系膜细胞fractalkine表达的影响
引用本文:魏琼,董莉,孙子林,刘必成,刘乃丰. 罗格列酮对糖基化终产物干预的人肾系膜细胞fractalkine表达的影响[J]. 中华内分泌代谢杂志, 2008, 24(6)
作者姓名:魏琼  董莉  孙子林  刘必成  刘乃丰
作者单位:东南大学附属中大医院,南京,210009
基金项目:江苏省中医药管理局科研项目,东南大学新进博士启动基金,东南大学校科研和教改项目 
摘    要:
观察罗格列酮和糖基化终产物对人肾系膜细胞fractalkine(FKN)表达的影响.结果 显示糖基化终产物能上调人肾系膜细胞的FKN表达,而罗格列酮能抑制糖基化终产物引起的FKN表达增加.

关 键 词:糖基化终产物,高级  糖尿病肾病  罗格列酮

On the expression of fractalkine by rosiglitazone in human renal mesangial cells induced by advanced glycation end products
WEI Qiong,DONG Li,SUN Zi-lin,LIU Bi-cheng,LIU Nai-feng. On the expression of fractalkine by rosiglitazone in human renal mesangial cells induced by advanced glycation end products[J]. Chinese Journal of Endocrinology and Metabolism, 2008, 24(6)
Authors:WEI Qiong  DONG Li  SUN Zi-lin  LIU Bi-cheng  LIU Nai-feng
Abstract:
The effect of rosiglitazone and advanced glycation end products (AGEs) on the expression of fractalkine in cultured human renal mesangial cells (HRMC) were investigated. Rosiglitazone inhibits the upregulation of fractalkine induced by AGEs in HRMC.
Keywords:Fractalkine
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