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Same-Day Repeat Hepatopulmonary Shunt Measurement during Planning Angiography for Hepatic Radioembolization
Institution:1. Department of Radiology, Icahn School of Medicine at Mount Sinai, Mount Sinai Hospital, New York, New York;2. Charlotte Radiology, Charlotte, North Carolina;1. Department of Diagnostic Imaging and Interventional Radiology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612;2. Department of Radiation Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612;3. University of South Florida, Morsani College of Medicine, Tampa, Florida;1. Department of Interventional Radiology, Royal Victoria Hospital, Barrie, Ontario, Canada;2. Department of Biology, Mount Allison University, Sackville, New Brunswick, Canada
Abstract:This report describes a technique for measuring lung shunt fraction (LSF) twice in a single session during planning arteriography for radioembolization using low and standard dose technetium-99m macroaggregated albumin (99mTc-MAA). A patient with a 16.0 cm hepatocellular carcinoma and LSF of 70% was treated with lenvatinib for 4 weeks. Planning arteriography with administration of 0.5 millicuries of 99mTc-MAA was then performed. Arterial access was maintained while the LSF was calculated, which was persistently elevated at 54%. Embolization of arteriovenous shunts was performed during the same session and 5.0 millicuries of 99mTc-MAA were administered. The repeat LSF was 29%. Successful radioembolization was subsequently performed.
Keywords:LSF"}  {"#name":"keyword"  "$":{"id":"kwrd0025"}  "$$":[{"#name":"text"  "_":"lung shunt fraction  technetium-99m macroaggregated albumin
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