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Activation of the classical complement pathway by BioRex-70
Authors:R J Vandenberg  S B Easterbrook-Smith
Affiliation:1. Department of Molecular Sciences, Macquarie University, Sydney, Australia;2. Biomolecular Discovery and Design Research Centre, Macquarie University, Sydney, Australia;3. Department of Molecular Medicine & Pathology, University of Auckland, Auckland, New Zealand
Abstract:
The cation exchange resin BioRex-70 was able to activate the classical complement pathway in human serum at 37 degrees C over the resin concentration range 0-5% (v/v). Using zymosan-treated human serum, it was found that the activation proceeded as far as complement protein C3.
Keywords:
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