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Contrast-enhanced cardiac MRI before coronary artery bypass surgery: impact of myocardial scar extent on bypass flow
Authors:Peter Hunold  Parwis Massoudy  Claudia Boehm  Thomas Schlosser  Kai Nassenstein  Stephan Knipp  Holger Eggebrecht  Matthias Thielmann  Raimund Erbel  Heinz Jakob  Jörg Barkhausen
Affiliation:(1) Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany;(2) Department of Thoracic and Cardiovascular Surgery, West German Heart Center Essen, University of Duisburg-Essen, Essen, Germany;(3) Department of Cardiology, West German Heart Center Essen, University of Duisburg-Essen, Essen, Germany
Abstract:The aim of the study was to relate the extent of myocardial late gadolinium enhancement (LGE) in cardiac MRI to intraoperative graft flow in patients undergoing coronary artery bypass graft (CABG) surgery. Thirty-three CAD patients underwent LGE MRI before surgery using an inversion-recovery GRE sequence (turboFLASH). Intraoperative graft flow in Doppler ultrasonography was compared with the scar extent in each coronary vessel territory. One hundred and fourteen grafts were established supplying 86 of the 99 vessel territories. A significant negative correlation was found between scar extent and graft flow (r = −0.4, p < 0.0001). Flow in grafts to territories with no or small subendocardial scar was significantly higher than in grafts to territories with broad nontransmural or transmural scar (75 ± 39 vs. 38 ± 26 cc min−1; p < 0.0001). In summary, the extent of myocardial scar as defined by contrast-enhanced MRI predicts coronary bypass graft flow. Beyond the probability of functional recovery, preoperative MRI might add value to surgery planning by predicting midterm bypass graft patency.
Keywords:Cardiac MRI  Contrast-enhanced MRI  Myocardial viability  Coronary artery disease  Coronary artery bypass graft  Doppler ultrasonography
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