The Japanese experience with metabolic imaging in the clinical setting |
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Authors: | Nagara Tamaki Koichi Morita Yuko Kawai |
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Institution: | (1) Department of Cardiology, Hokko Memorial Hospital, Sapporo, Japan;(2) Department of Nuclear Medicine, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, 060-8638 Sapporo, Japan |
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Abstract: | Conclusions Reduced utilization of fatty acids at rest often is observed in severely ischemic myocardium and possibly postischemic myocardium
despite normal perfusion at rest. The role of metabolic imaging in identifying postischemic insult as ischemic memory imaging
has been the focus of recent investigations. A number of reports from Japan show quite acceptable diagnostic accuracy of BMIPP
imaging for detecting coronary patients without prior MI. In addition, recent data indicate that BMIPP imaging has prognostic
value when applied in patients with documented or suspected coronary disease. The major advantage of BMIPP imaging is to demonstrate
ischemic myocardium as an area of altered metabolism at rest. Thus this study is of clinical importance for elderly patients
or for patients not suitable for a stress study. Furthermore, this radiopharmaceutical tracer may hold promise in demonstrating
early alteration of energy metabolism in a variety of myocardial disorders. |
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