Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses’ Health Study 2 |
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| Authors: | A. M. Drucker J. M. Thompson W.‐Q. Li E. Cho T. Li E. Guttman‐Yassky A. A. Qureshi |
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| Affiliation: | 1. Department of Dermatology, Warren Alpert Medical School, Providence, RI, USA;2. Department of Dermatology, Rhode Island Hospital, Providence, RI, USA;3. Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA;4. Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA;5. Laboratory for Investigative Dermatology, Rockefeller University, New York, NY, USA;6. Department of Dermatology and the Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA |
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| Abstract: | We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, the Nurses’ Health Study 2. We used logistic regression to calculate age‐ and multivariate‐adjusted odds ratios to determine the risk of incident AA and vitiligo associated with AD diagnosed in or before 2009. A total of 87 406 and 87 447 participants were included in the AA and vitiligo analyses, respectively. A history of AD in 2009 was reported in 11% of participants. There were 147 incident cases of AA and 98 incident cases of vitiligo over 2 years of follow‐up. AD was associated with increased risk of developing AA (OR 1.80, 95% CI 1.18–2.76) and vitiligo (OR 2.14, 95% CI 1.29–3.54) in multivariate models. In this study of US women, AD was associated with increased risk of incident vitiligo and AA in adulthood. |
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| Keywords: | alopecia areata atopic dermatitis comorbidities epidemiology vitiligo |
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