肺炎患儿检测肺炎支原体抗体和血清总IgE的临床价值

目的：探讨肺炎患儿检测肺炎支原体（Mycoplasma pneumoniae， MP）抗体和血清总IgE的临床价值。方法收集我院614例住院肺炎患儿及50例非肺炎患儿，进行血清MP抗体和总IgE检测，并以MP抗体结果将肺炎患儿分为阴性组、低滴度组和高滴度组，并对检测结果进行统计学分析。结果肺炎患儿各组及对照组总IgE阳性率和检测水平差异均有统计学意义（P均＜0．01）；肺炎患儿各组总IgE阳性率和检测水平均高于对照组，且差异均有统计学意义（P均＜0．01）；且肺炎患儿各组总IgE阳性率和检测水平随着MP抗体滴度的增高而增高，各组间两两比较，差异均有统计学意义（P均＜0．01）。肺炎患儿MP 抗体滴度与血清总 IgE 阳性率和检测水平均呈高度正相关（R2＝0．957，R2＝0．918，P 均＜0．01）。结论血清MP抗体和总IgE联合检测能为临床MP肺炎诊断和治疗提供相关依据。

Clinical value of Mycoplasma pneumoniae antibody and total serum IgE detection in children patients with pneumonia

[Abastract] Objective To investigate the clinical value of Mycoplasma pneumoniae （MP） antibody and serum total IgE detecting in children patients with pneumonia. Methods 614 cases of hospitalized chil-dren patients with pneumonia and 50 cases children patients without pneumonia were collected. The levels of serum MP antibody and total IgE were detected. The patients with pneumonia were divided into negative group , low litter group and high litter group, and the results were analyzed statistically. Results There were statisti-cal significance in the differences of positive rates and levels of total IgE among pneumonia each group and control group （Pall〈0.01）. The positive rates and levels of total IgE in pneumonia each group were all higher than that of control group,and the differences all had statistical significance（Pall〈0.01）. The positive rates and levels of total IgE all raised along with the MP antibody litter rising in pneumonia each group , and the differ-ences between each two groups all had statistical significance （Pall〈0.01）. The positive rates and levels of total IgE all had positive correlation with MP antibody litter （R2=0.957,R2=0.918,Pall〈0.01）. Conclusion The combined detection of serum MP antibody and total IgE can provide the basis for diagnosis and treatment of MP pneumonia.