甘精胰岛素治疗老年2型糖尿病口服药物控制不佳的临床观察

目的探讨甘精胰岛素（来得时）治疗老年2型糖尿病口服药物效果不佳时的疗效。观察治疗前后血糖、糖化血红蛋白、血脂、体质量变化、低血糖发生情况等指标变化。方法选择38例老年2型糖尿病患者,在使用口服药物血糖控制不理想（FBG〉10.0mmol/L）的基础上加用来得时治疗,随访3个月。结果治疗后患者三餐前后血糖,睡前血糖、糖化血红蛋白均较治疗前明显下降（P〈0.01）,体质量变化不大,低血糖发生率低。结论老年2型糖尿病口服药物不达标时,应用来得时,可以有效控制血糖,平稳达标,低血糖发生率低。

Clinical Observation of Insulin Glargine Treatment of Elderly Type 2 Diabetic Oral Drugs in Poorly Controlled

Objective To investigate insulin glargine（Lantus） in treating elderly patients with type 2 diabetes mellitus oral drug effect is poor curative effect.Blood glucose,glycosylated hemoglobin were observed before and after treatment,serum lipid,body weight changes,incidence of hypoglycemia in the changes of indexes.Methods 38 cases of elderly patients with type 2 diabetes,in the use of oral drug suboptimal glycemic control（FBG10.0mmol/L） based on the use of Lantus therapy,follow-up of three months.Results after treatment of patients with blood glucose after meals,bedtime blood glucose,glycosylated hemoglobin were significantly decreased（P0.01）,weight change,lower incidence of hypoglycemia.Conclusion in elderly type 2 diabetes mellitus oral medication compliance,use of Lantus,can effectively control blood sugar,stable standards,lower incidence of hypoglycemia.