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Intramedullary pilocytic astrocytomas — a clinical and morphological study after combined surgical and photon or neutron therapy
Authors:Rauhut  Friedhelm  Reinhardt  Volker  Budach  Volker  Wiedemayer  Helmut  Nau  Heinz-Eugen
Affiliation:(1) Department of Neurosurgery, University Hospital Essen, Essen, West Germany;(2) Institute of Neuropathology, University Hospital Essen, Essen, West Germany;(3) Department of Radiotherapy, University Hospital Essen, Essen, West Germany;(4) Neurochirurgische Klinik, Universitätsklinikum Essen, Hufelandstraße 55, D-4300 Essen 1, West Germany
Abstract:
Ten patients suffering from intramedullary pilocytic astrocytomas (WHO-classification: astrocytoma grade I) were investigated catamnesticly. Combined surgery and radiotherapy was performed. Seven patients received neutron irradiation postoperatively. In four cases the neurological symptoms were improved after follow-up periods ranging from 33 to 89 months. The three other patients died after 6 to 21 months. The autopsy findings of a 14 year old child are presented. Our results are compared with reports in the literature. In addition, long-term problems of the spinal column are discussed. It seems that the combined surgical and neutron therapy improves the prognosis of pencil gliomas.
Keywords:Astrocytoma  autopsy findings  complications  intramedullary neoplasm  long-term results  neutron therapy  pilocytic astrocytoma  spinal tumors  surgical tumor therapy  vertebral column
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