硫酸镁治疗室上性快速心律失常

作者用硫酸镁治疗室上性快速心律失常25例,结果:阵发性室上性心动过速10例中6例作终止治疗,4例显效,4例作预防性治疗,3例好转;紊乱性房性心动过速3例于治疗后1小时至2日内纠正;快速房颤4例在治疗后半小时内心室率得到缓解;非阵发性交界区心动过速8例在治疗后10小时至2日内纠正。表明硫酸镁为治疗室上性快速心律失常的一种有效制剂。

Clinical Effects of Magnesium Sulfate in the Treatment of Supraventricular Tachyarrhythmia

The obvious effects of magnesium sul-fate are noticed not only in ventriculartachyarrhythmia but also in supraventricu-lar tachyarrhythmia (SVTA) which includeparoxysmal supraventricular tachycardia(PSVT), chaotic atrial tachycardia (CAT),atrial fibrillation (AF) with rapid heart rateand nonparoxysmal juctional tachycardia(NPJT). This paper reports the effects ofmagnesium sulfate treatment in 25 cases ofSVTA in a self-controlled before and afterstuuy. Among 10 cases of PSVT, 6 cases weretreated by inJection of 25% magnsium sul-fate 5-10 ml. Except 2 cases with W-P-Wand aberrant ventricular condition, the PS-VT were terminated immediately after halfa dose of magnesium sulfate i.v.in 2 cases,other 2 cases were terminated by 5-10 minafter a dose of magnesium sulfate i.v. .Someimprovements were observed in these 4cases. The rest 4 cases were prevented by12 days' intravenous infusion of 1% magne-sium sulfate 250 ml per day, 3 cases of themrecovered. Three cases of CAT recovered withinan hour to two days by infusion of 1% mag-nesium sulfate 250 ml. Four case of AF with rapid heart ratewere collected, even though it is difficultto determine wheher it is due to overdoseor inadequacy of digitalis. The heart rateswere reduced by magnesium sulfate injec-tion in those 4 cases. Eight cases of NPJT due to heart fai-lure with digitalis intoxication recoveredafter infusion of 1% magnesium sulfate250ml within 10 hours to two days. Finally, the mechanism of the effect ofmagnesium sulfate treatment in SVTA wasdiscussed.