Molecular cloning and characterization of feline cellular genetic sequences homologous to the oncogene of the McDonough strain of feline sarcoma virus |
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| Authors: | J S Verbeek P de Ruyter H P Bloemers W J Van de Ven |
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| Affiliation: | Molecular Oncology Section, Department of Biochemistry, University of Nijmegen, Nijmegen, The Netherlands |
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| Abstract: | ![]()
The organization within the cat genome of cellular genetic sequences homologous to the viral oncogene v-fms of the McDonough strain of feline sarcoma virus (SM-FeSV) was determined. Four cosmid clones containing overlapping v-fms homologous cellular DNA inserts representing a contiguous region of cellular DNA of approximately 80 kbp in length have been isolated from a feline cosmid gene library. Within this region of the cat genome, the c-fms genetic sequences are dispersed over a region of around 30 kbp and are interspersed with at least three intervening sequences. |
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| Keywords: | Author to whom requests for reprints should be addressed. |
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