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丝裂霉素C与5—Fu用于抗青光眼滤过性手术的对比研究
引用本文:张德秀 泽浩. 丝裂霉素C与5—Fu用于抗青光眼滤过性手术的对比研究[J]. 临床眼科杂志, 1996, 4(4): 206-208
作者姓名:张德秀 泽浩
作者单位:西安医科大学第一附属医院眼科!710061(张德秀),日本京都府立医科大学眼科(泽浩,和田直树)
摘    要:
采用随机、双讯,前瞻对照的方法比较了丝裂霉素C(MMC)和5-氟尿嘧啶对难治性青光眼小梁切除手术的安全性和有效性。39例病人随机分成二组,一组使用MMC,另一组使用5-Fu。结果提示:(1)MMC组手术成功率高于5-Fu组;(2)MMC组角膜上皮缺损发生率,结膜创口渗漏率明显低于5-Fu组。

关 键 词:青光眼 外科手术 丝裂霉素C 5-氟尿嘧啶

A Comparative study on mitomycin C and 5 -Fluorouracil when used for glaucoma filtrable operation
Zhang Dexiu,et al. A Comparative study on mitomycin C and 5 -Fluorouracil when used for glaucoma filtrable operation[J]. Journal of Clinical Ophthalmology, 1996, 4(4): 206-208
Authors:Zhang Dexiu  et al
Affiliation:First Affiliated Hospital Xian Medical Uniuersity. 710061
Abstract:
This paper reports the safety and effectivenss of Mitomycin C and 5 -Fluorouracil when administered after the removal of trabecula to cure difficult glaucoma,with the method of random selection of patients with blindness in both eyes. 39 patients were randomly divided into two groups,the first group of 20 eyes administered with Mitomycin C,while the second group of 19 eyes with 5-Fluorouracil. The result showed that: l.In the Mitomycin C group, the rate of success of operation is higher than the 5-fluorouracil group;2. The rate of the occurrence of epithelial lesion and the leak of trauma in the conjunctiva is lower that the 5 - Fluorouracil group.
Keywords:Mitomycin C   5-Fluorouracil   filtration   eye-pressure   complications
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