| 基质金属蛋白酶与动脉粥样硬化 |
| |
| 引用本文： | 沈琳,马亚兵,高海青. 基质金属蛋白酶与动脉粥样硬化[J]. 中国心血管杂志, 2005, 10(1): 69-71 |
| |
| 作者姓名： | 沈琳 马亚兵 高海青 |
| |
| 作者单位： | 山东大学齐鲁医院老年病科,山东,济南,250012 |
| |
| 摘 要： | 基质金属蛋白酶 (MMP)降解细胞外基质 (ECM ) ,参与动脉粥样硬化 (AS)的细胞外基质重构过程 ,与AS的形成、斑块破裂及再狭窄密切相关。适度调节金属蛋白酶的活性为防治AS提供了新的靶点。
|
| 关 键 词： | 基质金属蛋白酶 动脉粥样硬化 细胞外基质 |
| 文章编号： | 1007-5410(2005)01-0069-03 |
| 修稿时间： | 2004-06-04 |
Matrix metalloproteinase and Atherosclerosis |
| |
| MA Ya-bing. GAO Hai-qing. Matrix metalloproteinase and Atherosclerosis[J]. Chinese Journal of Cardiovascular Medicine, 2005, 10(1): 69-71 |
| |
| Authors: | MA Ya-bing. GAO Hai-qing |
| |
| Affiliation: | MA Ya-bing. GAO Hai-qing. Department of Senior Hearth Care,Qilu Hospital of Shandong University,Jinan 250012,China |
| |
| Abstract: | Matrix metalloproteinases hydrolyze components of the extracellular matrix, and participate in the process of extracellular matrix remodeling in atherosclerosis. It is closely related with atherosclerosis progression, plaque rupture and restenosis. Appropriate regulation of the activity of matrix metalloproteinases offers a new target for preventing and curing the atherosclerosis. |
| |
| Keywords: | Matrix metalloproteinase Atherosclerosis Extracellular matrix |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
