| 肿瘤型M2丙酮酸激酶与癌类抗原19-9联合检测在胰腺癌诊断中的应用 |
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| 引用本文： | 周娟,王东,陈连周,曾文涛,傅茜,黄晓卉.肿瘤型M2丙酮酸激酶与癌类抗原19-9联合检测在胰腺癌诊断中的应用[J].实用医学杂志,2005,21(20):2252-2254. |
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| 作者姓名： | 周娟 王东 陈连周 曾文涛 傅茜 黄晓卉 |
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| 作者单位： | 1. 510010,广州军区广州总医院肿瘤科
2. 510080,广州市,中山大学附属第一医院外科实验室 |
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| 摘 要： | 目的:探讨肿瘤型M2丙酮酸激酶(TumorM2-PK,TuM2-PK)、糖类抗原19-9(CA19-9)在胰腺癌中的表达特性。方法:采用ELISA法分别检测50例胰腺癌患者、35例胰腺炎患者及80名健康体检人血中TuM2-PK、CA19-9含量。结果:胰腺癌患者血中TuM2-PK、CA19-9值分别是(164.9±41.3)U/mL、(630.1±200.3)U/mL。在胰腺癌的诊断中单独检测时TuM2-PK、CA19-9敏感性分别为75%、74.5%,特异性分别为90%、85%,联合测定敏感性、特异性分别达到82.3%、100%。结论:联合检测TuM2-PK、CA19-9有助于提高对胰腺癌诊断的特异性和敏感性。
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| 关 键 词： | 丙酮酸激酶 胰腺肿瘤 |
| 收稿时间： | 2005-05-20 |
| 修稿时间： | 2005-05-20 |
Application of tumor M2 pyruvate kinase and cancer antigen 19-9 in pancreatic cancer |
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| ZHOU Juan,WANG Dong,CHEN Lian-zhou,ZEN Wen-tao,FU Qian,Huang Xiao-hui.Application of tumor M2 pyruvate kinase and cancer antigen 19-9 in pancreatic cancer[J].The Journal of Practical Medicine,2005,21(20):2252-2254. |
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| Authors: | ZHOU Juan WANG Dong CHEN Lian-zhou ZEN Wen-tao FU Qian Huang Xiao-hui |
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| Institution: | ZHOU Juan,WANG Dong,CHEN Lian-zhou,ZEN Wen-tao,FU Qian,Hua ng Xiao-hui. Department of Oncology,Guangzhou General Hospital of Guangzho u Military,Guangzhou 510010,China |
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| Abstract: | Objective To discuss the expression characteristic of tu mo r M2-PK(TuM2-PK) and CA19-9 in pancreatic cancer. Methods The serum TuM2- PK and CA19-9 were measured by ELISA in 50 pancreatic cancer patients, 35 pan creatitis patients and 80 healthy people. Results Serum TuM2-PK and CA19-9 c oncentration of pancreatic cancer patients were ( 164.88± 41.33) U/mL, ( 63 0.1± 200.3) U/mL, A similar sensitivity was observed for TuM2-PK (75% ) a nd CA19-9(74.5% ) in pancreatic cancer. And TuM2-PK showed more specifici... |
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| Keywords: | Pyruvate kinase Pancreatic neoplasms |
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