|
|||||
|
|
| ImmuKnowTM-Cylex检测技术在肾移植术后重症肺炎中的应用研究 | |
| 引用本文： | 吴琳,王瑾,王庆华,唐敏英,尚乐乐,谭建明. ImmuKnowTM-Cylex检测技术在肾移植术后重症肺炎中的应用研究[J]. 福建医科大学学报, 2011, 45(4): 267-269 |
| 作者姓名： | 吴琳 王瑾 王庆华 唐敏英 尚乐乐 谭建明 |
| 作者单位： | 吴琳 (解放军南京军区福州总医院,福建省移植生物学重点实验室,福州,350025) ； 王瑾 (解放军南京军区福州总医院,福建省移植生物学重点实验室,福州,350025) ； 王庆华 (解放军南京军区福州总医院,福建省移植生物学重点实验室,福州,350025) ； 唐敏英 (解放军南京军区福州总医院,福建省移植生物学重点实验室,福州,350025) ； 尚乐乐 (解放军南京军区福州总医院,福建省移植生物学重点实验室,福州,350025) ； 谭建明 (解放军南京军区福州总医院,福建省移植生物学重点实验室,福州,350025) ； |
| 基金项目： | 福建省科技创新平台建设计划项目 |
| 摘 要： | 目的 探讨ImmuKnowTM-Cylex检测技术能否作为肾移植术后发生肺部感染的预警指标.方法 收集17例肾移植受者的肝素钠抗凝全血46份,通过测量CD4+T细胞刺激后释放的ATP浓度来判定机体细胞免疫水平.结果 肾移植术后重症肺炎发生前(移植术后两周内)组CD4+T细胞ATP值为(383.47±186.51)ng/... |
| 关 键 词： | 肾移植 肺炎 免疫,细胞 移植免疫学 |
The Clinical Study of ImmuKnowTM-Cylex Test to Predict Severe Pneumonia in Kidney Transplant Recipients |
|
| WU Lin,WANG Jin,WANG Qinghua,TANG Minying,SHANG Lele,TAN Jianming. The Clinical Study of ImmuKnowTM-Cylex Test to Predict Severe Pneumonia in Kidney Transplant Recipients[J]. Journal of Fujian Medical University, 2011, 45(4): 267-269 | |
| Authors: | WU Lin WANG Jin WANG Qinghua TANG Minying SHANG Lele TAN Jianming |
| Affiliation: | WU Lin,WANG Jin,WANG Qinghua,TANG Minying,SHANG Lele,TAN Jianming Department of Fujian Provincial Key Laboratory of Transplant Biology,Fuzhou General Hospital,Fuzhou 350025,China |
| Abstract: | Objective To evaluate whether ImmuKnowTM-Cylex test could be used to predict the occurrence of severe pneumonia in kidney transplant recipients.Methods 46 heparinized blood samples were taken from 17 kidney transplant recipients.Cell-mediated immunity(CMI) was assessed by measuring the concentration of ATP released from CD4+T cells following stimulation.One-way ANOVA test were used for analysis of data.Results The mean ATP concentration in the transplant recipients with SP was(187.2±115.15)ng/mL,significantly lower than that before the occurrence of SP(383.47±186.50)ng/mL and that after recovering from SP(427.78±177.43)ng/mL(P<0.05).Conclusion ImmuKown assay is a valuable tool in monitoring immune status in kidney transplant recipients and predicting the occurrence of severe pneumonia. |
| Keywords: | kidney transplant pneumonia immunity cellular transplantation immunology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |