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胸水和血清肿瘤标志物检测在肺癌诊断中的应用价值
引用本文:张成宪,毛中圆,苏天雄. 胸水和血清肿瘤标志物检测在肺癌诊断中的应用价值[J]. 当代医学, 2021, 27(9): 100-102. DOI: 10.3969/j.issn.1009-4393.2021.09.038
作者姓名:张成宪  毛中圆  苏天雄
作者单位:甘肃省庆阳市人民医院检验科,甘肃 庆阳 745000;甘肃省庆阳市人民医院检验科,甘肃 庆阳 745000;甘肃省庆阳市人民医院检验科,甘肃 庆阳 745000
摘    要:目的 探讨胸水和肿瘤标志物在肺癌患者诊断中的应用价值.方法 选取本院2017年6月至2019年6月收治的80例肺癌伴胸水患者作为肺癌组,并选择同期住院的肺炎、脓胸、肺结核、慢性阻塞性肺疾病患者80例为非肺癌对照组,检测两组胸水和血清肿瘤标志物水平变化.结果 肺癌组胸水、血清肿瘤标志物CEA、CA199、CA153、CA...

关 键 词:肺癌  胸水  肿瘤标志物

The value of detection of pleural fluid and surem tumor markers in the diagnosis of lung cancer
ZHANG Chengxian,Mao Zhongyuan,SU Tianxiong. The value of detection of pleural fluid and surem tumor markers in the diagnosis of lung cancer[J]. Contemporary Medicine, 2021, 27(9): 100-102. DOI: 10.3969/j.issn.1009-4393.2021.09.038
Authors:ZHANG Chengxian  Mao Zhongyuan  SU Tianxiong
Affiliation:(Department of Clinical Laboratory,People's Hospital of Qingyang,Qingyang,Gansu,745000,China)
Abstract:Objective To explore the value of pleural fluid and surem tumor markers in the diagnosis of lung cancer.Methods From June2017 to June 201980 cases of lung cancer with pleural effusion patients in our hospital were selected as lung cancer group,and 80 patients with pneumonia,empyema,tuberculosis,and chronic obstructive pulmonary disease who were hospitalized during the same period were selected as the nonlung cancer control group.The changes in the levels of pleural fluid and surem tumor markers in the two groups were detected.Results Lung cancer group of hydrothorax tumor markers CEA,CA199,CA153,CA125 levels were significantly higher than the control group(P<0.01),in lung cancer group pleural effusion tumor markers area under the ROC curve>serum tumor markers of the area under the ROC project were CA199,CA153,CA125,SCC,CEA had similar area under the ROC curve of pleural effusion and serum tumor markers in the lung cancer group.Conclusion Pleural effusion(CEA,CA199,CA153,CA125)and serum(CEA)tumor markers have good application value in the diagnosis of lung cancer patients,and tumor markers in pleural effusion have higher auxiliary diagnostic value than tumor markers in serum.
Keywords:Lung cancer  Pleural fluid  Tumor markers
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