2015至2018年骨科伤口感染患者病原菌分布及耐药性分析

目的 对骨科伤口采样培养,进行病原菌分布和耐药情况分析,为临床合理使用抗菌药物提供依据.方法 回顾性分析本院骨科2015年至2018年送检伤口分泌物的细菌培养及药敏结果 .结果 2835份标本中,细菌培养阳性516例,阳性率为18.20％;其中格兰阴性杆菌291例,占56.40％,主要为铜绿假单胞菌、阴沟肠杆菌、大肠埃...

Analysis on the distribution and drug resistance of pathogenic bacteria for patients with wound infection in orthopedics from 2015 to 2018

Objective To analyze the distribution and drug resistance of pathogenic bacteria by sampling and culture the secretion of wounds in orthopedics,so as to provide basis for clinical rational use of antibacterial drugs.Methods The bacterial culture and drug sensitivity results of wound secretions submitted by Orthopedics Department of our hospital from 2015 to 2018 were retrospectively analyzed.Results Among the 2835 specimens,516 were positive for bacterial culture,with positive rate of 18.20%.Among them,there were 291 cases(56.40%)for Gram negative bacilli,mainly including Pseudomonas aeruginosa,Enterobacter cloacae,Escherichia coli and Klebsiella pneumoniae.212 cases(41.09%)were Gram-positive cocci,mainly including Staphylococcus aureus,coagulase negative Staphylococci and Enterococcus faecalis.In addition,there were 13 cases of fungi,accounting for 2.51%.Staphylococcus aureus had good sensitivity to various antibacterial drugs.Among them,the sensitivity rate to linezolid,tigecycline,teicoplanin and vancomycin reached 100%,and the drug resistance of Pseudomonas aeruginosa and Klebsiella pneumoniae in Gram-negative bacilli was good.However,there was severe drug resistance for Escherichia coli and Enterobacter cloacae,and their drug resistance rate to various antibacterial drugs could reach 50%,especially the drug resistance rate of Enterobacter cloacae to cephalosporins can reach 100%.Conclusion The distribution of pathogenic bacteria for patients with wound infection in orthopedics is complex,and the drug resistance situation remains still to be serious.More active and effective measures should be taken to control the increase and spread of drug-resistant bacteria.