抑郁症中医证候的临床流行病学调查

目的:探讨抑郁症中医证候特征,明确各证候的诊断依据,为新药临床试验中中医证候诊断标准的主、次症的确定提供参考,为构建辨证方法新体系提供依据。方法:对100例抑郁症患者进行中医证候的临床流行病学调查。结果:研究显示抑郁症患者最常见的症状分别是精神抑郁、神疲、烦躁、面色异常、睡眠质量差等,这些症状的发生率均在95%以上;患者以肝气郁结和肝郁脾虚型最为多见,二者所占的百分比均为35%,其次为心胆气虚型和忧郁伤神型。结论:治疗抑郁症患者时要着重改善其主要症状,应重点从肝论治,同时注意调理脾胃。

Clinical Epidemiology Investigation on Sydroms of Depression

Objective:To investigate the sydrome characteristics of depression,determine the diagnosis Standards of the syndrome and provide reference for the diagnosis of syndrome in clinical trial,which will help to construct new system for differentiation of syndromes.Methods: The patients was selected from out-patient and hospital-patient from Sep,2005 to Nov,2005 in the affiliated hospital of LNTCM for clinical epidemiology investigation.Results: The studies shows the most common symptoms demonstrated were depression,the god weary,agitation,the abnormal facial color,the bad sleep quality,etc,with the rate above 95%;the most common syndromes were Impeded Flow of Liver-qi,hepatic stagnation and splenic deficiency,with the rate of 35%,next for deficiency of heart and gallblader,melancholily beingnerve-racking.Conclusion: Great emphasis should be put on improving the main symptoms of depression patients,treating specially from liver,simultaneously pays attention to the spleen and stomach.