MTX腹腔镜下注射与中药联合治疗宫外孕的研究

目的:探讨腹腔镜下MTX局部注射并口服中药联合保守治疗对宫外孕保留生育功能的疗效。方法:将60例非破裂性宫外孕患者随机分成2组,分别进行腹腔镜下MTX局部注射加口服中药和腹腔镜下输卵管造口术,比较成功率、HCG转阴时间及输卵管复通率和妊娠率。结果:2组的成功率无显著性差异,联合保守治疗组HCG转阴时间较对照组长,差异有显著性(P<0.05);而联合保守治疗组输卵管复通率和妊娠率分别为77.78%、57.14%,较对照组分别为60%、40%提高,差异有显著性(P<0.05〉。结论:本中西医结合疗法为最大限度保留生殖功能的新方法。

The Research on Ectopic Pregnancy Treated by Methotrexate Abdominal Speculum Injection Method Combination with Chinese Crude Drug

Objective:To investigate the efficacy of preserving reproductive function by conservative therapy of combining laparoscopy and Chinese Medicine for ectopic pregnancy. Methods:60 patients of unruptured ectopic pregnancy were randomly divided into two groups. One group had been treated conservatively by combining laparoscopy with Chinese Medicine. After confirmatory diagnosis was made under laparoscope, low dose(5~15mg) of methotrexate(MTX) was injected into tubal swelling,as well as taking Chinese Medicine orally. Another group had been treated with salpingstomy by laprosopy. The differences were compared in successful rate,the mean time of hCG turning negative, tubal pantency rate and pregnancy rate in two groups. Results:There was no significant difference in successful rate in two groups. The mean time of hCG turning negative of combined therapy is longer than that of control group(P <0.05).The tubal pantency rate and pregnancy rate were 77.78%?60.00% and 57.14%? 40.00% respectively in conserved group and control group,with significant difference. Conclusions: This combined therapy was a simple and safe method which could preserve reproductive function to the maximum.