耐万古霉素肠球菌感染的临床分析

目的探讨耐万古霉素肠球菌感染的易感因素及防治方法。方法对我院2011年50例耐万古霉素肠球菌感染的病例进行回顾性调查分析。结果耐万古霉素肠球菌感染患者中以院内感染较多,感染部位以下呼吸道为主,多伴有耐药葡萄球菌,同时培养阳性。结论强效广谱抗菌药物的大量应用是耐万古霉素肠球菌感染的重要危险因素。治疗可交替使用β-内酰胺类、氨基糖苷类及喹诺酮类抗菌药物;严格的隔离消毒措施可防止该感染在医院内蔓延。

Clinical analysis of vancomycin-resistant enterococcus infection

Objective To evaluate the sensitive factors of infection by vancomycin-resistant enterococcus（VRE） as well as the corre-sponding prevention strategies .Methods Investigation and analysis were conducted for 30 cases of infection induced by VRE .Re-sults Some of the patients had been infected in communities ,but most of the patients had been infected in hospitals .The main in-fection site was lower respiratory tract ,together with the positive results of drug-resistant staphylococci culture .Conclusion Using large amount of strong effect broad-spectrum antibiotics is the major risk factor causing infection by VRE .Alternative use of β-lactam antibiotics ,amino-glycosides or quinolones can cure the infection .Besides ,strict isolation and disinfection measures can pre-vent the infection from spreading in hospital .