人参败毒丸的药效学研究

目的:研究人参败毒丸(羌活、柴胡、人参等)的解热,抗炎,镇痛,抗菌作用.方法:采用伤寒、副伤寒甲、乙菌苗所致兔发热模型观察药物的解热作用,角叉菜胶致大鼠足跖肿胀法,用小鼠扭体法了解其镇痛作用,采用体外抗菌法.结果:人参败毒丸能明显降低实验性动物体温;1.5 g·kg-1有显著的抗炎作用;对醋酸所致小鼠扭体反应有明显镇痛、抗菌效果.结论:人参败毒丸在上述作用中优于人参败毒散,具有解热,抗炎,镇痛,抗菌作用.

Pharmacodynamic of Renshenbaidu Pills

AIM: To study antipyretic, anti-inflammtory, analgesia and antisepsis effect of Renshenbaidu Pills.(Rhizouia Seu Radix Notopterygii, Radix Bupleuri, Radix Ginseup, etc) METHODS: The antipyretic effect of the pills was observed using rabbits fever model carrageenine caused foot swelling of rat, analgesic effect was tested by the method of writhes of mice, the method was applied antibacterial in vitro. RESULTS: Renshenbaidu Pills remarkably brought down the body temperature in experimental animal with fever 1.5 g/kg of Renshenbaidu Pills had the obvious anti-inflammatory effect and notable analgesic action on the reaction of writhes of mice induced by acestic acid, it had antisepsis effect. CONCLUSION: Renshenbaidu Pills are better than Renshenbaidu Powder, it has antiyretic, antiinflammatory, analgesia and antisepsis effects.