氩离子凝固术联合质子泵抑制剂治疗Barrett食管的疗效分析

目的观察内镜下氩离子凝固术（APC）联合抑酸治疗Barrett食管（BE）的临床疗效。方法选择2009年1月至2011年12月周口市中心医院消化科经过病理证实的BE的患者30例，行内镜下氩离子凝固术治疗，并于术后给予质子泵抑制剂治疗，分别于术后2、6、12个月后进行随访复查，评价其疗效及不良反应。结果所有患者手术进行顺利且无并发症，27例为1次治疗病灶完全清除，3例2次治疗病灶完全清除，12个月后复查无一例复发。结论应用APC联合质子泵抑制剂治疗BE的方法简便易行、安全，患者易耐受，费用经济，适合在地市级及部分条件好的县级医院开展和普及。

Efficacy Analysis of Argon Plasma Coagulation combined Proton Pump Inhibitor Therapy of Barrett's Esophagus

Objective To observe the clinical efficacy of endoscopic argon plasma coagulation （APC） combined with proton pump inhibitor in the treatment of Barrett esophagus （BE）. Methods We selected 30 patients with Barrett esophagus （BE）. These patients with histologically proved BE selected from Zhoukou Central Hospital from January 2009 to December 2011.They were treated with endoscopic argon plasma coagulation, and let them oral proton pump inhihitors in after operation. We followed up of these patients after 2 months, 6 months and 12 months.And we evaluated the curative effect and adverse reaction. Results All patients＇ surgery carded out smoothly, with no complications, Lesions in 27 patients after the first treatment to be completely removed, Lesions in 3 patients after second times of treatment to be completely removed. All patients patients had no relapse 12 months after treatmend. Conclusion Application of APC combined with proton pump inhibitor in the treatment of BE was simple, safe, economics, and the patient could tolerate. It could develop and popularize in municipal hospitals and some good conditions hospitals in county hospitals.