| COX-2在骨肉瘤中的表达及其临床意义 |
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| 引用本文： | 黄建军,石莺,向志刚. COX-2在骨肉瘤中的表达及其临床意义[J]. 医学理论与实践, 2008, 21(10): 1134-1135 |
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| 作者姓名： | 黄建军 石莺 向志刚 |
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| 作者单位： | 吉首大学医学院,湖南省吉首市,416000 |
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| 摘 要： | 目的:检测37例骨肉瘤组织中COX-2的表达,分析其对骨肉瘤的临床诊断及预后的意义。方法:应用免疫组化方法对37例骨肉瘤组织中COX-2进行检测。结果:37例骨肉瘤组织中有32例COX-2表达阳性,其表达与骨肉瘤分期和有无转移相关(P<0.05),与肿瘤组织学类型无相关性。结论:COX-2与骨肉瘤的发生及预后存在一定的相关性,可为骨肉瘤的临床诊断和预后判断提供帮助。
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| 关 键 词： | 骨肉瘤 环氧化酶-2 |
The Expression of COX-2 in Osteosarcoma and Its Clinical Significance |
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| HUANG Jianjun,SHI Ying,XIANG Zhigang. The Expression of COX-2 in Osteosarcoma and Its Clinical Significance[J]. The Journal of Medical Theory and Practice, 2008, 21(10): 1134-1135 |
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| Authors: | HUANG Jianjun SHI Ying XIANG Zhigang |
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| Affiliation: | ( The Medical College of Jishou University, Hu＇ nan Province 416000 ) |
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| Abstract: | Objective:To investigate the expression of COX-2 in 37 cases of osteosarcoma and analyse its significance in diagnosis and prognosis of osteosarcoma.Methods:Immunohistochemical strain was used to detect the expression of COX-2 in 37 cases of osteosarcoma.Results:From 37 cases COX-2 was positive in the 32.The expression of COX-2 was related to the metastasis and grade,had no relation to the category.Conclusion:COX-2 is related to the generation and prognosis,it may be an indicator for clinical diagnosis and prognosis of osteosarcoma. |
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| Keywords: | Osteosarcoma Cyclooxygenase-2(COX-2) |
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