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^13C-呼气试验检测胃排空的原理及其结果分析
引用本文:黄晓璐,曲新华,蔡铭慈,陈志威,严惟力,熊屏.^13C-呼气试验检测胃排空的原理及其结果分析[J].胃肠病学,2009,14(6):375-377.
作者姓名:黄晓璐  曲新华  蔡铭慈  陈志威  严惟力  熊屏
作者单位:1. 上海交通大学医学院附属第九人民医院超声学科,200011
2. 上海交通大学医学院附属仁济医院核医学科
基金项目:国家自然科学基金,上海教委科技创新项目,上海交通大学医学院科研基金 
摘    要:随着稳定性核素^13C-呼气试验检测胃排空临床应用的普及,与其相关的问题也日益突出。作为一种间接测定胃排空的定量手段.理解试验原理和解读试验结果对临床工作者尤为重要。本文通过全面阐述^13C-呼气试验的原理、与其他胃排空检测方法的比较、试剂种类以及胃排空呼气试验底物^13C-辛酸和^13C-乙酸在体内的代谢以及^13C-的转运和分布规律,以期能帮助临床工作者理解^13C-呼气试验的原理并分析试验结果。

关 键 词:放射性核素  呼气试验  胃排空  方法学

Principle of 13C-Breath Test and Analysis of Test Results in Evaluating Gastric Emptying
HUANG Xiaolu,QU Xinhua,CAI Mingci,CHEN Zhiwei,YAN Weili,XIONG Ping.Principle of 13C-Breath Test and Analysis of Test Results in Evaluating Gastric Emptying[J].Chinese Journal of Gastroenterology,2009,14(6):375-377.
Authors:HUANG Xiaolu  QU Xinhua  CAI Mingci  CHEN Zhiwei  YAN Weili  XIONG Ping
Institution:.( Department of Ultrasound, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai,200011)
Abstract:With the development and widespread use of stable nuclide ^13C-breath test in evaluating gastric emptying, its relative problems are emerging gradually. As an indirect quantifieational tool for measuring gastric emptying, it is important to understand the principle of ^13C-breath test and analyze the test results properly in clinical practice. This article aimed to elucidate the principle of ^13C-breath test, and to compare with the other gastric emptying methods, types of testing reagent, metabolism of breath test substrate ^13C-oetanoic/acetate acid, the transit and distribution of ^13C etc., so as to help the clinicians to understand the principle and results of ^13C-breath test.
Keywords:Radionuclides  Breath Test  Gastric Emptying  Methodology
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