低分子肝素治疗充血性心力衰竭高凝状态的临床观察

目的探讨低分子肝素对充血性心力衰竭高凝状态的治疗作用。方法所有充血性心力衰竭高凝状态的患者均接受常规治疗,治疗组(30例)加用低分子肝素针5000u/(次.d),皮下注射,7d为1个疗程;对照组(30例)不加用低分子肝素针。结果治疗组总有效率90.3%,对照组总有效率73.3%,P<0.05;与对照组相比,血红蛋白、红细胞压积差异有显著性,P<0.01;血小板聚集率、纤维蛋白原差异具有显著性,P<0.05。结论低分子肝素对充血性心力衰竭高凝状态具有治疗作用。

Clinical observation of the congestive heart - failure with hypercoagulability treated by low molecular heparin

Objective To explore the therapeutic action of the congestive heart-failure with hypercoagulability by low molecular heparin.Methods All the congestive heart-failure with hypercoagulability patients were accepted the routine treatment.Thirty patients in the treatment group were treated with low molecular heparin injection(5000~u,qd),hypodermic injection for 7 days as a course.And thirty patients were treated without low molecular heparin injection as control group.Results The total effective rate of the treatment group was 90.3% and the control group was 73.3%(P<0.05).The treatment group compared with the control group in hemoglobin and hematocrit was significant difference(P<0.01).In platelet aggregation rate and fibrinogen,with difference(P<0.05).Conclusion There is therapeutic action in the congestive heart-failure with hypercoagulability by low molecular heparin.