2010年滨州市手足口病的流行病学特点及其临床治疗

目的 调查手足口病患者的流行病学特点和治疗进展,从而为及时控制疫情,提高治愈率,降低病死率提供依据.方法 对滨州市人民医院2010年住院的1680例手足口病例进行流行病学调查.结果 2010年手足口病流行季节在5～9月,6～7月为发病高峰.发病年龄集中在1～5岁,占住院病例数的83.93％.男性明显多于女性,男女性别比为1.58∶1.散居儿童发病率明显高于托幼机构.重症手足口病病例EV71阳性率最高,占65.31％.结论 手足口病发病与年龄、季节密切相关.EV71感染所致手足口病重症病例发生率高,部分病例病情凶险易导致死亡,但及早识别重症病例,优化治疗方案可有效提高手足口病治愈率、降低病死率.

Epidemiological characteristics and clinical treatment of hand, foot and mouth disease in Binzhou city in 2010

Objective To investigate the epidemiological characteristics and treatment of hand, foot and mouth disease（HFMD）, and provide evidence to control the epidemic, improve the cure rate and decrease the mortality. Melhods Epidemiological investigation was conducted in 1680 HFMD patients in Binzhou City People＇ s Hospital in 2010. Results The epidemic season of HFMD in 2010 was from May to September, and the morbidity peak months were June and July. The peak age of onset was between 1 and 5 years（83.93%）. Male affected was more often than female （1.58：l）. The incidence rate in scattered children was obviously higher than children in nurseries and kindergartens. The EV71 positive rate was 65.31% in the children with severe HFMD. Conclusions HFMD is correlated with age and season. The most severe HFMD patients are caused by EV71 infection. Therefore, the cure rate can be improved and the mortality can be decreased by early recognition of HFMD severe cases and optimize therapeutic scheme.