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Genomic analyses detect Eurasian‐lineage H10 and additional H14 influenza A viruses recovered from waterfowl in the Central United States |
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| Authors: | Anthony C. Fries Jacqueline M. Nolting Andrew S. Bowman Mary L. Killian David E. Wentworth Richard D. Slemons |
| Affiliation: | 1. Department of Veterinary Preventive Medicine, The Ohio State University, , Columbus, OH, USA;2. Department of Evolution, Ecology and Organismal Biology, The Ohio State University, , Columbus, OH, USA;3. National Veterinary Services Laboratories, USDA, APHIS, , Ames, IA, USA;4. Virology, J. Craig Venter Institute, , Rockville, MD, USA |
| Abstract: | The accurate and timely characterization of influenza A viruses (IAV) from natural reservoirs is essential for responses to animal and public health threats. Differences between antigenic and genetic subtyping results for 161 IAV isolates recovered from migratory birds in the central United States during 2010–2011 delayed the recognition of four isolates of interest. Genomic sequencing identified the first reported Eurasian‐origin H10 subtype in North America and three additional H14 isolates showing divergence from previously reported H14 isolates. Genomic analyses revealed additional diversity among IAV isolates not detected by antigenic subtyping and provided further insight into interhemispheric spread of avian‐origin IAVs. |
| Keywords: | H10 subtype H14 subtype influenza A virus migratory birds surveillance |