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结直肠癌辅助化疗进展
引用本文:张冬梅. 结直肠癌辅助化疗进展[J]. 医学综述, 2008, 14(9): 1334-1336
作者姓名:张冬梅
作者单位:天津市第五中心医院肿瘤科,天津,300450
摘    要:
结直肠癌辅助化疗经历了探索、争论近30年,先后确认5-FU/Lev和5-FU/CF为DukesC期结直肠术后标准的辅助化疗方案。随着新药奥沙利铂、伊立替康、卡培他宾、S-1等的上市,结肠癌的辅助化疗又登上了一个新台阶。口服卡培他宾可代替静脉注射5-FU/CF方案;FOLFOX优于5-FU/CF,有可能确立为DukesC期结肠癌术后标准的辅助化疗方案;靶向药物的诞生和免疫治疗有良好势头。

关 键 词:结直肠癌  辅助化疗
文章编号:1006-2084(2008)09-1334-03
修稿时间:2007-09-10

Advance of Colorectal Carcinoma Adjuvant Chemotherapy
ZHANG Dong-mei. Advance of Colorectal Carcinoma Adjuvant Chemotherapy[J]. Medical Recapitulate, 2008, 14(9): 1334-1336
Authors:ZHANG Dong-mei
Affiliation:ZHANG Dong-mei.(Center of Clinical Oncology,Tianjin Fifth Center Hospital,Tianjin,300450,China)
Abstract:
Chemotherapy for colorectal carcinoma had been argued about for nearly three decades.5-Fu/Lev and 5-Fu/CF were regarded as standard adjuvant chemotherapy regiment for Dukes'C colorectal cancer.Great progress has been made after many new anti-cancer agent,such as oxaliplatin,irinotecan,and capecitabine were found effective.Oral capecitabine matches that of venous administration of 5-FU/CF;FOLFOX is superior to and may take the place of 5-FU/CF in the standard adjuvant chemotherapy,and FOLFIRI seems to be bet...
Keywords:Colorectal carcinoma  Chemothrerapy  
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