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Experimental study on the apoptosis of the astrocytes and the oligodendrocytes induced by Ca^2+ reperfusion
引用本文:马海涵,邵阳,伍亚民,李宏运,廖维宏,刘媛,杨恒文,曾琳,龙在云. Experimental study on the apoptosis of the astrocytes and the oligodendrocytes induced by Ca^2+ reperfusion[J]. 中华创伤杂志(英文版), 2002, 5(1): 32-35
作者姓名:马海涵  邵阳  伍亚民  李宏运  廖维宏  刘媛  杨恒文  曾琳  龙在云
作者单位:ResearchInstituteofSurgery,DapingHospital,TheThirdMilitaryMedicalUniversity,Chongqing400042
摘    要:


关 键 词:细胞凋亡 星形细胞 少突神经胶质细胞 再灌注 CNS 钙离子

Experimental study on the apoptosis of the astrocytes and the oligodendrocytes induced by Ca2+ reperfusion
Haihan Ma,Yang Shao,Yamin Wu,Hongyun Li,Weihong Liao,Yuan Liu,Hengwen Yang,Lin Zeng,Zaiyun Long. Experimental study on the apoptosis of the astrocytes and the oligodendrocytes induced by Ca2+ reperfusion[J]. Chinese journal of traumatology, 2002, 5(1): 32-35
Authors:Haihan Ma  Yang Shao  Yamin Wu  Hongyun Li  Weihong Liao  Yuan Liu  Hengwen Yang  Lin Zeng  Zaiyun Long
Affiliation:Research Institute of Surgery, Daping Hospital, The Third Military Medical University, Chongqing 400042, China
Abstract:
OBJECTIVE: To investigate the apoptosis rules of the astrocytes and oligodendrocytes induced by Ca(2+) reperfusion. METHODS: The apoptosis of purified cultured astrocytes and oligodendrocytes induced by Ca(2+) reperfusion and the relationship between the development of the cell apoptosis and post-reperfusion time was observed. RESULTS: Both the astrocytes and oligodendrocytes were obviously in a time-dependent fashion, and the apoptosis ratios of the oligodendrocytes (39.73%+/-4.16%) were higher than the astrocytes (19.64%+/-4.67%) 24 hours after Ca(2+) reperfusion. The TUNEL positive cells were 13.6+/-1.82 and 21.4+/-1.95 at every visual field of astrocytes and oligodendrocytes respectively 24 hours after Ca(2+) reperfusion. CONCLUSIONS: The astrocytes and oligodendrocytes are similar wi th the development rules on apoptosis and have different susceptiveness to the situation.
Keywords:Astrocytes  Oligodendrocytes  Apoptosis
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