多模式分子影像PET-MRI的研究进展

PET-CT已成为当今恶性肿瘤诊断、分期及疗效评价必不可少的工具,但是,MRI具有比CT更好的软组织分辨力,还可提供多种生理功能、多序列和多参数成像,且无放射性损伤,其与PET提供的分子信息互补、融合,有望成为新的双模式显像工具,在基础和临床研究中将起着至关重要的作用.然而PET与MRI结合在技术上具有很多挑战,近几年...

Progress in PET-MRI multimodality molecular imaging

PET-CT multimodality imaging has become an essential tool for diagnosis,staging and therapeutic evaluation for malignancy.But MRI has better soft tissue resolution than CT,and provides a variety of functional imaging,multi-sequence and multi-parameter imaging,and has no radiation damage.The integration of plentiful information from MRI and molecular information provided by PET is expected to become a new dual-mode imaging tool which will play a very important role in basic and clinical research.However,many challenges are existed in the combined PET and MRI technology,and it has become a focus in molecular imaging research in recent years,and has made significant progress.This paper overviews the progresses of PET-MRI integration technologies and devices,preliminary applications and multimodality probes.