| 下体负压作用下心血管系统某些变化的机制探讨 |
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| 引用本文： | 王德汉,张其吉,赵国璇,赵元准,麻淑清,王芳琳.下体负压作用下心血管系统某些变化的机制探讨[J].航天医学与医学工程,1988(2). |
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| 作者姓名： | 王德汉 张其吉 赵国璇 赵元准 麻淑清 王芳琳 |
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| 作者单位： | 航天医学工程研究所 北京
(王德汉，张其吉，赵国璇，赵元准，麻淑清)，航天医学工程研究所 北京(王芳琳) |
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| 摘 要： | 在-4kPa 下体负压作用下,测定35只开胸麻醉犬的血压、左室内压,冠状动脉血流,心电图和心外膜电图;测定了注入利血平,阿托品、异丙肾上腺素及葡萄糖右旋糖酐的被麻醉家兔的血压,心电图和心率,并处死动物,电镜观察心肌组织。结果表明,心电图ST—T 变化是与冠状动脉血流减少、心肌缺血和植物性神经系统功能状态有关。增加交感神经系统活性和血容量可提高对负压的耐力。负压时发生的心肌细胞内线粒体与毛细血管的变化是可以恢复的。
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| 关 键 词： | 下身负压 耐受性 冠状血管 血容量 超微结构 |
Study of Mechanism of Changes in Cardiovascular System Under Lower Body Negative Pressure |
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| Wang Dehan.Study of Mechanism of Changes in Cardiovascular System Under Lower Body Negative Pressure[J].Space Medicine & Medical Engineering,1988(2). |
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| Authors: | Wang Dehan |
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| Abstract: | This study was carried out with anesthetized rabbits and dogs
exposed to lower body negative pressure (-4kPa).The ECG,BP,
HR,LVSP,CBF and epicardiumgram were measured.Myocardial cells
were observed using an electromicroscope.The changes of the ST-T
segment in ECG were correlated with the reduction of the coronary
blood flow,myocardium ischemia and state of the autonomic nervous
system.The tolerance to LBNP were enhanced when the bloo volume
and sympathetic nervous activity were increared.The ultrastructure
of myocardial cells Changed under LBNP could recover. |
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| Keywords: | low body negative pressure tolerance coronary artery blood volume ultrastructure |
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