红芽大戟化学成分研究

目的研究茜草科植物红芽大戟(Knoxia corymbosa Willd．)的化学成分。方法利用硅胶、聚酰胺等色谱技术分离纯化,根据化合物的理化性质和光谱数据进行鉴定。结果从红芽大戟的正丁醇萃取部分分离得到4个黄酮醇苷成分,分别鉴定为:槲皮素-7-O-α-L-阿拉伯糖-3-O-β-D-6″-乙酰基吡喃葡糖苷(quercetin-7- O-α-L-arabinosyl-3-O-β-D-6″-acetylglucopyranoside,1);山奈酚-7-O-α-L-阿拉伯糖-3-O-β-D-吡喃葡糖苷(kaempferol-7-O-α-L-arabinosyl-3-O-β-D-glucopyranoside,2);槲皮素-3-O-β-D-吡喃葡糖苷(quercetin-3-O-β-D-glucopyranoside,3); 槲皮素-3-O-β-D-6″-乙酰基吡喃葡糖苷(quercetin-3-O-β-D-6″-acetylglucopyranoside,4)。结论化合物1为新化合物,其余均为首次从该种植物分到。

Studies on the chemical constituents of Knoxia corymbosa

AIM: To study the chemical constituents of Knoxia corymbosa Willd. METHODS: Chromatography was used to isolate and purify the chemical constituents, their structures were identified by spectral analysis. RESULTS: Four flavonol glycosides were identified as quercetin-7-O-alpha-L-arabinosyl-3-O-beta-D-6"-acetylglucopyranoside (1), kaempferol-7-O-alpha-L-arabinosyl-3-O-beta-D-glucopyranoside (2), quercetin-3-O-beta-D-glucopyranoside (3), quercetin-3-O-beta-D-6"-acetylglucopyranoside (4). CONCLUSION: Compound 1 is a new flavonol glycoside. The other flavonol glycosides were isolated from Knoxia corymbosa Willd for the first time.