108例皮肤转移性恶性肿瘤临床病理分析

目的 探讨皮肤转移癌发生规律。以利正确诊断。方法 收集、复习和分析108例皮肤转移癌病例的临床和病理学资料。结果 108例中男65例，女43例，发病年龄平均49.8岁，发生部位依次为腹部，胸部。肩背部，腰臀部，头颈部，四肢，会阴，外阴及全身，患者出现皮肤肿块到就诊的时间平均为3.5个月；皮肤转移癌出现在原发瘤诊断后平均16.2个月；肿瘤最大直径以2-5cm常见，常见原发癌部位男性为肺，大肠，胃，原发部位不明和食道；女性中依次为乳腺，大肠，卵巢，肺和原发部位不明。结论 与癌发病率一致。高发癌出现皮肤转移率高；皮肤转移癌出现在原发癌附近皮肤处较多；有癌症史患者出现皮肤结节应怀疑皮肤转移癌的可能。

A Clinicopathological Analysis of 108 Cases of Malignant Tumors with Skin Metastasis

Objective To explore the rules of skin metastasis so as to make correct diagnoses. Methods The clinical and pathological data of 108 cases with skin metastasis were collected, reviewed and analyzed.Results There were 65 male and 43 female among those 108 cases, with an average age of 49 8 years. The metastasis occurring regions in turn were abdomen, chest, shoulder-back, waist-glutea, head-neck, extremities, perineum, vulva and whole body. The average time of the appearance from skin mass to diagnosis was 3 5 months. Skin metastasis occurred at mean 16 2 months after diagnosis of primary tumor. The commonest sites of original tumor were lung, large intestine, stomach, unknown primary site and esophagus in male,breast, large intestine, ovary, lung and unknown primary site in female respectively.Conclusions In consistent with cancer morbidity,the cancer with high incidence has a high skin metastasis rate. Skin metastasis often appeared on the skin near primary lesion. It should be suspected to skin metastasis,if skin nodule appears on patient with cancer history.