| 人乳腺珠蛋白与乳腺癌 |
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| 引用本文： | 郭建秀,刘秀娜,胡川闽.人乳腺珠蛋白与乳腺癌[J].国外医学(肿瘤学分册),2006(11). |
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| 作者姓名： | 郭建秀 刘秀娜 胡川闽 |
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| 作者单位： | 第三军医大学检验医学系临床生化教研室，第三军医大学检验医学系临床生化教研室，第三军医大学检验医学系临床生化教研室 |
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| 基金项目： | 重庆市科委自然科学基金资助项目(2004BA5017) |
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| 摘 要： | 人乳腺珠蛋白(hMAM)是乳腺组织特异性表达的分泌性蛋白,目前被认为是一种具有临床应用前景的乳腺肿瘤标志物。现就MAM在乳腺癌肿瘤免疫治疗中的应用、作为乳腺癌肿瘤标志物的诊断现状和存在问题等方面探讨MAM在乳腺癌肿瘤疫苗的设计、诊断及转移检测的作用。
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| 关 键 词： | 珠蛋白 乳腺肿瘤 免疫逃逸 肿瘤标记 生物学 |
Human mamaglobin and mammary carcinoma |
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| GUO Jian-xiu.Human mamaglobin and mammary carcinoma[J].Foreign Medical Sciences (Cancer Section),2006(11). |
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| Authors: | GUO Jian-xiu |
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| Institution: | GUO Jian-xiu. Department of Clinical Biochemistry College of Laboratory Medicine,the Third Military Medical University,Chongqing 400038,China |
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| Abstract: | Human mammaglobin (MAM), a secretary glycoprotein specifically expressed in mammary tissue,is considered as a promising marker for breast cancer in clinical research. This article reviews the effects and current status of this molecule in the immunotherapeutic vaccine design, diagnosis and metastatasis monitoring of breast cancinoma and some conflicts in its application. |
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| Keywords: | Globin Mammary neoplasms Escape of immune surveillance Tumor markers biology |
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