广西地区艾滋病患者认知功能初步调查

目的 了解广西地区艾滋病患者的认知功能.方法 选择广西南宁市第四人民医院根据实验室确诊的艾滋病患者80例作为病例组 ;同时从陪同家属中选取近3个月内无可感染艾滋病病毒的危险行为 ,艾滋病病毒抗体检测阴性88例作为对照组 ,应用蒙特利尔认知评估量表(MoCA)的中文翻译版 ,对两组对象进行认知功能调查及评估.结果 病例组总分为2~29分 ,平均(20 .04 ± 6 .13 )分 ,其中认知功能损害48例(60 .00% );对照组总分为17~29分 ,平均(25 .02 ± 2 .98 )分 ,其中认知功能损害6例(6 .82% ).病例组MoCA量表总分、视觉与执行力、命名、延迟回忆、注意力、抽象能力及定向力项得分均低于对照组(P＜0 .01).两组对象在各得分段人员分布及比例方面比较 ,差异有统计学意义(P＜0 .05).对性别、年龄、文化程度3个因素进行了Logistic回归分析 ,只有文化程度是影响因素.结论 艾滋病患者中存在不同程度的认知功能损害 ,文化程度可能是影响该量表得分的因素 .

Preliminary survey on cognitive function of AIDS patients in Guangxi area

Objective To understand the cognitive function of the patientwith acquired immune deficiency syndrome (AIDS) in Guangxi are.MethodEighty caseof AIDconfirmed by laboratory in the Nanning Fourth People′Hospital were selected athe patientgroup ;athe same time 88 individualwithouthe dangeroubehaviorwithin 3 monthwhich could cause human im-munodeficiency virus(HIV) infection and with negative anti-HIV antibody detection were selected from the accompanying family memberathe control group .The Chinese translation version of the Montreal cognitive assessmenscale (MoCA) waadopted to conducthe investigation and evaluation on the cognition function in the two group.ResultThe total score span in the patientgroup wa2-29 pointwith the average of (20 .04 ± 6 .13) point,of normal cognitive function and 48 cases(60 .00% ) of cognitive impairmen;the total score span in the control group wa17-29 pointwith the average of (25 .02 ± 2 .98) point,of normal cogni-tive function and 6 cases(6 .82% ) of cognitive impairmen.The scoreof MoCtotal score ,visual and execution ,naming ,delayed recall ,attention ,abstraction and orientation in the patientgroup were lowethan those in the control group ,the differencebetween the two groupwere statistically significan(P＜0 .01) .The personnel distribution and proportion in the variouscore segmenta-tionhad statistical differencebetween the two group(P＜0 .05) .The factorof gende,age and educational level were performed the Logistiregression analysi,the resultshowed thaonly the educational level wathe influencing facto.Conclusion Differendegreeof cognitive impairmenexisin the AIDpatientand the educational level may be factoaffecting the scale score .