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| 乙型肝炎后肝硬化患者胆结石形成的机制探讨 | |
| 引用本文： | 冯青青,樊拖迎,李春安,幸军. 乙型肝炎后肝硬化患者胆结石形成的机制探讨[J]. 东南国防医药, 2011, 13(3): 217-218 |
| 作者姓名： | 冯青青 樊拖迎 李春安 幸军 |
| 作者单位： | 解放军94医院消化科,江西南昌,330002 |
| 摘 要： | 目的探讨乙型肝炎后肝硬化(简称肝硬化)患者胆结石之患病率以及血清雌二醇(E2)、高密度脂蛋白胆固醇(HDL-C)和总胆红素(TBil)在胆结石形成机制中的作用。方法分析住院男性肝硬化患者胆结石的患病率。测定肝硬化胆结石患者(68例)和无胆结石患者(120例)血清E2、HDL-C、TBil以及胆囊壁厚度和胆囊横径水平变化,并进行相关分析。结果肝硬化A级患者胆结石患病率为7.9%(3/38)、B级27.5%(22/80)、C级61.4%(43/70)。肝硬化胆结石组血清E2、TBil、胆囊厚度和胆囊横径均明显高于肝硬化无胆结石组,而HDL-C低于无胆石组(P<0.01)。肝硬化胆结石组血清E2水平与TBil和胆囊横径、胆囊壁厚度明显正相关,与高密度脂蛋白胆固醇呈负相关(P<0.05)。结论男性肝硬化患者胆结石患病率与病情程度密切相关;肝硬化患者血清E2、HDL-C和TBil水平变化在胆结石形成中发挥重要作用。 |
| 关 键 词： | 肝硬化 乙型肝炎 胆结石 雌二醇 高密度脂蛋白胆固醇 胆红素 |
Mechanism of gallstone formation in patients with cirrhosis after hepatitis B |
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| FENG Qing-qing,FAN Tuo-ying,LI Chun-an,XING Jun. Mechanism of gallstone formation in patients with cirrhosis after hepatitis B[J]. Journal of Southeast China National Defence Medical Science, 2011, 13(3): 217-218 | |
| Authors: | FENG Qing-qing FAN Tuo-ying LI Chun-an XING Jun |
| Affiliation: | FENG Qing-qing,FAN Tuo-ying,LI Chun-an,XING Jun.Department of Digestive Disease,94 Hospital of PLA,Nanchang,Jiangxi 330002,China |
| Abstract: | Objective To explore the incidence of gallstones in patients with the cirrhosis after hepatitis B and the role of serum estradiol(E_2),high-density lipoprotein cholesterol(HDL-C),and bilirubin in gallstone formation.Methods The incidence of gallstones in male patients at the hospital with post-hepatitis B cirrhosis was analyzed.The serum level of E_2,HDL-C,TBil and the thickness of bladder wall and transverse diameter were measured in 68 cases with cirrhosis and in 120 cases without cirrhosis.Results The in... |
| Keywords: | cirrhosis hepatitis B gallstones estradiol high-density lipoprotein cholesterol bilirubin |
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