脊柱转移瘤手术治疗的生活质量随访

目的 从生活质量及肿瘤学预后方面探讨外科手术对脊柱转移瘤的治疗价值.方法 2004年3月～2009年1月,对36例行前路或后路减压内固定术的脊柱转移瘤患者进行随访,手术前后的生活质量应用埃德蒙顿症状评估量表(Edmonto symptom assessment scale,ESAS)进行评定.结果 截至2009年7月...

Quality of life in surgical treatment of spinal metastases

Objective To evaluate the efficacy of surgery in patients with spinal metastases with respect to quality of life and oncology prognosis.Methods From March 2004 to January 2009,36 consecutive patients underwent anterior or posterior decompression and internal fixation for spinal metastases were evaluated.Pre-and postoperative quality of life of the patients were evaluated with the Edmonton symptom assessment scale（ESAS）.Results All patients survived 6-36 months until the final follow-up（July 2009）,the average survival time was 15.2 months with 8 patients still alive at the final follow-up.The neurological function was obviously improved in 68% cases.After surgery,the total score of the ESAS significantly improved in 30 successfully evaluated patients,and the largest improvement was noted in the domain of pain.There were also significant improvements noted in the domains of well-being,tiredness,appetite,anxiety,nausea and drowsiness.But no obvious changes in terms of depression and shortness of breath.Conclusion For patients with solitary spinal metastasis,low-malignant primary tumor and the Tokuhashi revised score of 12-15 points,surgical management brings about a positive effect on the overall quality of life,and the greatest benefit occurrs in the pain reduction.